What is Pittsburgh compound b used for?
Pittsburgh compound B (PiB) is a radioactive analog of thioflavin T, which can be used in positron emission tomography scans to image beta-amyloid plaques in neuronal tissue. Due to this property, Pittsburgh compound B may be used in investigational studies of Alzheimer’s disease.
Is PiB FDA approved?
Our analysis utilized PiB, a beta-amyloid radiotracer widely used in research which is not FDA approved for clinical use and which requires an on-site cyclotron for production due to its short half-life.
What does PiB PET measure?
PIB PET was used to assess the density of beta-amyloid senile plaques by binding to them (Klunk et al., 2004).